What worked for me: create /lib/systemd/system-sleep/touchpad : #!/bin/sh case $1 in post) /sbin/rmmod psmouse && /sbin/modprobe psmouse ;; esac make file executable chmod +x /lib/systemd/system-sleep/touchpad and test (suspend computer and wake-up again) Solution from: https://unix.stackexchange.com/questions/309247/linux-mouse-freezes-after-suspend